The framework of the MAIN Consortium is based on the existence of highly integrated Programs and Facilities (core - others) that, albeit interconnected and supervised by the Steering Committee (see below), will be enabled to independently manage and financially support their strategic initiatives. This is a necessary choice, as the Consortium is composed of a large number of investigators and relies on a number of initiatives, each comprising homogeneous tasks and common strategic objectives. Each Program/Facility is coordinated by a Principal Investigator and a Co-principal Investigator (TDP: Dejana and Vestweber; TIP: Pardi and Sanchez-Madrid; TVP: Ridley and Rorth; TEP: Wolf and Moser; Imaging: Grohovaz and Dunlap; Proteomics: Bachi and Alessio; Microarrays: Alcalay and Muller; Bioinformatics: Zvelebil and Yang). They will appoint a Program/Facility Committee, composed of three to four members representing the other initiatives, to oversee the activities of their specific initiative and to promote and coordinate the efforts required to achieve the Program/Facility specific goals. The coexistence within each Committee of members of the other initiatives will ensure proper coordination of efforts among the various Programs’ and Facilities’ strategic plans. This is particularly relevant for the Facilities’ Principal Investigators, as they will have to be kept abreast of the needs of each Program. The Committees will interact on a regular basis (twice a month) and via the video-conferencing system and will plan two extended meetings a year to appraise progress in the respective Initiative.
A second level of organization and management of the Consortium is based on the existence of Local Institutional Coordinators (LIC), who represent the participating Institutions and sit on the Steering Committee. LICs will be coordinating locally the activities of the Consortium, and will be the Consortium delegates operating peripherally to ensure proper management at the level of the individual participating Institutions.