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Main-Noe Students Meeting - May 17-20th 2008, Certosa di Pontignano, Italy

MAIN Annual Conference, October 2007

MAIN LIC's Meeting, 9th March, 2007

MAIN Students' Meeting, 19th-22nd May, 2007

SEMM Workshop on Cell Migration: From Molecules to Organisms and Diseases

MAIN Science News: Paper published on "A novel protein on cells of the blood vessel w

 
 
NEWS
Main-Noe Students Meeting - May 17-20th 2008, Certosa di Pontignano, Italy
Deadline for applications: 24 February 2008

Application form

DATE: Saturday, May 17th to Tuesday, May 20th, 2008 (ending Monday 19th late c.10.30pm).

Tel: +39-0577-354 71
Fax: +39-0577-354 740
E-mail: mazzeschi@unisi.it certosa@unisi.it
Web: www.unisi.it/servizi/certosa

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MAIN Annual Conference, October 2007
[url=http://www.main-noe.org/index.php?module=mnconference3]CLICK HERE TO ACCESS THE CONFERENCE BOOKING FORM[/url]

[url=http://www.main-noe.org/upload/Plano_Metro_2007.pdf]metro plan[/url]

DATE: 18th-20th October, 2007 in Madrid:

Thursday 18th (Welcome Buffet Dinner @ 20.30)
Conference all day Friday 19th-to & including lunch on Saturday 20th.
EAB, LIC's, Scientific Officer & External Reviewer's Meetings post-lunch
to c. 17.00.

LOCATION: Hotel Jardin Metropolitano
Reina Victoria 12, 28003 Madrid, Spain

Contact: Yolanda Garcìa
Tel: 0034911831810
Fax: 0034911831811
e-mail: metropolitano@vphoteles.com
http://www.bookings.org/hotel/es/jardin-metropolitano.en.html?aid=307713

Please CLICK HERE for the BOOKING FORM


Located in Avenida Reina Victoria, next to Cuatro Caminos Square & underground station and only 5 minutes from Paseo de la Castellana.

Transport from the Airport:

UNDERGROUND: Take the underground from Barajas Airport to Nuevos Ministerios Stop, and then change line to the Cuatro Caminos station (1 stop, see map: ). The Hotel is just by the Underground.
The underground ticket prices from T1, T2 and T3 of Barajas Airport are: 1 Euro and from the T4 are 2 Euros. There are also underground/bus tickets valid for 10 trips, which cost 6.40 Euros.

TAXIS: There is taxi service available from terminals at Barajas Airport.
The taxi fares range between 25-30 Euros, depending on the traffic. From the train station the taxi fares are a little lower, given that it is nearer the city center.

BUS: There are buses from all Terminals at Barajas Airport to Avenida de America and Plaza de Colon. Once there, you can take the underground to reach the hotel. From Avenida de America there is a direct underground line (line 6) to the hotel (Cuatro Caminos stop).

Transport from the Train Station:

From Chamartin Station, in the North of Madrid, you can take the underground to the Cuatro Caminos stop.
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MAIN LIC's Meeting, 9th March, 2007
The next Local Institute Co-Ordinator's Meeting will take place on Friday 9th March at the Hotel Dei Cavalieri, Milan, Italy.
The meeting will be held from 9am-1pm followed by a quick post-meeting lunch.
Location: Hotel Dei Cavalieri
Piazza Missori 1
20123 Milano
Tel.: + 39 02 8857 287
Fax: + 39 02 8857 241
E-mail: congress@hoteldeicavalieri.com
Nearest stations: MM3 Missori; MMI Duomo
Hotel Dei Cavalieri Location, please then click on “How to Reach Us”
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MAIN Students' Meeting, 19th-22nd May, 2007

The MAIN STUDENTS’ MEETING will take place at the EUROTEL VICTORIA VILLARS, route des Layeux, CH-1884 Villars-sur-Ollon in Switzerland.

DATE:  Saturday, May 19th to Tuesday, May 22nd, 2007 (ending late on Monday 21st  c.10.30pm).

CLICK HERE TO GO TO THE APPLICATION FORM

The hotel is situated in the centre of Villars & located 5 minutes walk from the station and 5 minutes walk from the cable car.
(by train: 1h15min from Lausanne; 2h15 min from Geneva Airport, 4h from Zurich Airport, 5 h from Milan (294 km), 81 km from Chamonix; 32 km from Montreux):

Tel.+41 (0)24 495 3131; Fax +41 (0)24 495 3953
E-mail: villars@eurotel.victoria.ch

Please see link: Eurotel Victoria

Maps: Villars Map


This dynamic and exclusive three day meeting will encompass a combination of poster presentations together with approximately 20 student presentations (mainly graduate students working in the Consortium) as well as specially selected guest speakers and Principle Investigators of the MAIN Consortium.

The meeting will be able to host 50 students and a group of leaders from the Consortium and is an excellent and unique opportunity to meet other students from the Consortium and network.
The idea is to have a plenary session the first evening by an invited speaker. Sunday and Monday would be covered by lectures given by senior researchers (45 to 60min) and contributions by the students (15 min talks). A trip is planned for Sunday afternoon.

We're delighted to announce that the four distinguished scientists who will be speaking are:

Prof. Fritz Krombach, Local Institute Co-Ordinator in MAIN, Ludwig Maximilians University, Munich (LMU)
Overall goals & achievements: Fritz Krombach

Prof. Timothy Elliot, Cancer Sciences Division, University of
Southampton, UK
Key subject areas: The intracellular assembly of class I MHC molecules and the role of cofactor proteins, The role of antigen glycosylation on processing and presentation, Recognition of post-translationally modified peptide epitopes, Regulatory T cells in tumour immunity
Prof. Timothy Elliott, Cancer Sciences Division

Prof. John H. Kehrl, Head, B-Cell Molecular Immunology Section, National Institute of Allergy & Infectious Diseases.
A major accomplishment of the B-Cell Molecular Immunology Section (BCMIS) was the identification of a family of proteins that regulate heterotrimeric G-protein signaling, which have been termed RGS proteins.
John H. Kehrl, M.D. Laboratory of Immunoregulation, NIAID, NIH

Dr. Marie-Claude Blatter, Swiss Institute of Bioinformatics. Part of the Swiss-Prot group in Geneva, headed by Amos Bairoch:SIB - Research Groups which develops and improves the UniProtKB/Swiss-Prot protein knowledgebase, the most widely used protein information resource. Its goal is to provide the worldwide Life Science community with the highest quality level of protein-related information.


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SEMM Workshop on Cell Migration: From Molecules to Organisms and Diseases

SEMM Workshop on Cell Migration:
From Molecules to Organisms and Diseases

Date: May 12th-14th, 2007

Location: IFOM-IEO Campus
                   Milano, Italy

The topics of the workshop are:
- CYTOSKELETON
- SIGNALLING AND SPATIAL INFORMATION
- MODEL ORGANISMS
- IMAGING
- DISEASES

Understanding how cells migrate contributes to elucidate various fundamental processes involved in normal and pathological conditions. A significant progress in unraveling the mechanisms underlying cell migration can only be achieved through a comprehensive approach spanning from the study of single molecules to model organisms and diseases. This workshop will provide the scientific community with a focused panel of discussion covering all the topical aspects of cell migration, with the ultimate aim to highlight future challenges, pressing questions and provide novel experimental models to address them.

This workshop is open to all scientists including PhD students and Postdocs.


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MAIN Science News: Paper published on "A novel protein on cells of the blood vessel w
Dietmar Vestweber,  at the University of Muenster and LIC in MAIN has had an article on
"A novel protein on cells of the blood vessel wall involved in the regulation of the opening of cell contacts"
published in the prestigious Journal of Experimental Medicine, July 2006.

Vestweber & his teams' overall scientific goals include: understanding how leukocytes overcome the barrier of the blood vessel wall & how various known and unknown cell adhesion mechanisms mediate and control the opening and closure of endothelial cell contacts and the movement of leukocytes through the contact sites between endothelial cells.
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MAIN Annual Conference, 6-8th October, 2006

BOOKING FORM

Location:
   Parc Hotel (4*)
                   via Brolo, 2/a
                   37014 Castelnuovo del Garda (VR)
                   (NB: Peschiera del Garda nearest station, 5 mins. by taxi)
                    Italy
                 
                   Tel.: 0039 045 64052011
                   Fax: 0039 045 64052020

Date:         6-8th October, 2006 (Friday 6th: Welcome Buffet Dinner, 8pm+
                                                        Saturday & Sunday 7th & 8th: Conference)

For more info on hotel, please see the  Parc Hotel website


The Conference itself will be run along similar lines to last year's, although there will be some alterations. The conference will include three poster sessions, which will be the core of the meeting and an ideal forum for discussion and appraisal of progress in the ongoing 20 Work Packages plus the four new Work Packages. There will not be a formal presentation of each poster but the PI or Researcher to whom the poster belongs in each session should remain nearby to answer any questions. We hope this will encourage a more relaxed and stimulating atmosphere for the exchange of ideas and comments. 

The poster sessions will be interspersed with three overviews sessions introduced by PIs/Researchers as appropriate. These will be highlighting the developments made in the ongoing extended & merged Work Packages as well as detailing the four new work packages. Work Packages discussed during the presentations will have their poster displayed in the preceding poster session (wherever possible).

The idea of this meeting is that the LICs, PIs & Researchers involved in all the current Work Packages in this NoE should attend this meeting to get together to discuss their progress. The first MAIN Annual Conference took place at San Raffaele Dibit, Milan (Sept. 30th- October 2nd, 2005) & was very successful.

On the final day of the Conference there will be a joint meeting of the Steering Committee (comprising all Local Institutional Coordinators), the External Advisory Board and the External Reviewer to discuss current problems and future plans. This will take place immediately after lunch & not last more than two hours. For all those not involved in the post-lunch meeting, the Conference will effectively finish at lunchtime on Sunday, 8th October.


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3rd Joint UK/German Adhesion Society Meeting London

DATE: Thursday 20th - Friday 21st July, 2006

Sir Alexander Fleming Building, Imperial College London, South Kensington Campus,Exhibition Road, London

Registration & Abstract Submission dates

Early registration and abstract submission deadline: Friday 12th May 

(125 euros/£75; 100 euros/£60 students)   Late registration: Friday 7th July 

(160 euros/£95; 125 euros/£75 students)

Organisers: Sussan Nourshargh (Imperial College London)                       Peter Friedl (University of Wurzburg)                       Sara Rankin (Imperial College London)                       Waldemar Kolanus (University of Bonn)CONTACT: Mrs Enid Goodman (Imperial College):                       e.goodman @ imperial.ac.uk


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MAIN Science News: Paper published on the role of caveolae in the migration of human
Anne Ridley, Vice Co-Ordinator of MAIN & Local Institute Co-Ordinator at the Ludwig Institute for Cancer Research (LICR), has had a paper published in Nature Cell Biology.

Anne's team's overall goal is to understand how inflammatory stimuli affect endothelial cell biology. In addition, they aim to elucide the signalling pathways activated in T cells and in endothelial cells following their interaction. The overall aim is to identify key signalling proteins that could be targets for therapeutic intervention in chronic inflammation.
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The Observatory for Micro & NanoTechnologies seminar: “NanoTechnologies for cell inve

DATE: 14th March 2006 in Paris

LOCATION: Institut Curie, 12 rue Lhomond, Paris 5ème.

Agenda is now available,please see the following link for all programme details: "Nanotechnologies for Cell Investigation "Seminar Programme details

and online registration is open at:  http://www.omnt.fr http://www.omnt.fr/

International experts will present the state of the art in the new field of "micro-nanotechnologies for cell biology". They will present methods for the manipulation of single cells, use of surface patterning to study the interactions of cells with solid substrates, measurement of biologically pertinent parameters by optical,  electrical or mechanical techniques at the scale of single cells and mimicking of cellular functions in artificial structures. Don’t miss this opportunity to get a complete and up-to-date picture of this exciting domain!

With the participation of:

Guenter Fuhr, Fraunhofer-Institut für Biomedizinische Technik (IBMT),Germany
Prof. Peter Fromherz, Max Planck Institute, Martinsried, Germany
Tejal Desai, Boston University, USA
Prof Pier Luigi Luisi, Professor Emeritus ETH-Zürich & Università degli Studi di Roma
Jon Cooper, Glasgow University, Scotland
Prof. Kishan Dholakia, St Andrews University, UK
Benoit Dubertret, ESPCI, Paris, France
Pascal Silberzan, Institut Curie, Paris, France
Michel Bornens, Institut Curie, Paris, France
Alexandra Fuchs, CEA/DSV, Grenoble, France
Véronique Baticle, CEA-BEM, Grenoble, France


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EMBO Workshop: Cell Migration, Tissue Invasion and Disease
DATE:         14 – 17 October, 2006
LOCATION
: Hotel La Palma, Capri, Italy

Organizers:
Sandro De Falco, Gabriella Minchiotti and M. Patrizia Stoppelli

IGB Meeting Coordinators:
M. Graziella Persico, Ingram I. Iaccarino & M. Patrizia Stoppelli

This meeting will cover the relevant aspects of signaling driving migration both during embryonic development and adult life as well as cell motility in invasion, inflammation and tissue engineering.

Speakers:

Kari Alitalo, Helsinki
Richard K Assoian, Philadelphia, PA
Paolo Bazzicalupo, Naples
Francesco Blasi, Milan
Paola Bovolenta, Madrid
Peter Carmeliet, Leuven
Giulio Cossu, Milan
Joe Culotti, Toronto, ON
Elisabetta Dejana, Milan
Barry Dickson, Vienna
Julian Downward, London
Dylan R. Edwards, Norwich
Frank B. Gertler Cambridge, MA
Jeffrey Hubbell, Zurich
Santa Jeremy Ono, London
Rudiger Klein, Martinsried
Michel Labouesse, Strasbourg
Salvador Martinez, Alicante
Christine Mummery, Utrecht
Denise Montell, Baltimore, MD
Paolo Netti, Naples
M. Angela Nieto, Madrid
Stefano Piccolo, Padova
Carola Ponzetto, Turin
Anne J. Ridley, London
Frederic Rosa, Paris
David Salomon, Bethesda, MD
Claudio Stern, London
Jean Paoul Thiery, Paris
Robert T. Tranquillo, Minneapolis, MN
David Wilkinson, London

Please see the following link for the meeting advert: EMBO Workshop
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MAIN Science News: “Follicular B Helper T Cells in Antibody Responses and Autoimmunit

Prof. Bernhard Moser of the Institute of Cell Biology, Switzerland and a Local Institute Co-Ordinator within the MAIN project, has had a paper on the subject

“Follicular B Helper T Cells in Antibody Responses and Autoimmunity”

published as a Research Article in Nature Reviews Immunology (November 2005)
http://www.nature.com/nri/journal/v5/n11/full/nri1714_fs.html

together with
Carola G. Vinuesa at the The John Curtin School of Medical Research, The Australian National University, Canberra, Australia;
Stuart G. Tangye at the Centenary Institute of Cancer Medicine and Cell Biology, Newton, Australia; and
Charles R. Mackay at The Garvan Institute of Medical Research, Sydney, Australia


(E-mail correspondence: bernhard.moser@izb.unibe.ch)


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"Deciphering the Cell Migration Code" Students' Meeting 2006

The STUDENTS’ MEETING will take place at the Gwatt-Zentrum in Switzerland.

DATE:  Saturday, May 13th to Tuesday, May 16th, 2006.

Located by the breathtaking Lake of Thun: at the Gwatt-Zentrum am Thunersee, CH-3645 Gwatt (Thun)
(30-40 km from Bern. Nearest stations: Spiez/Thun-c. 8km)

Tel. 033 334 30 30, Fax 033 334 30 31
mail@gwatt-zentrum.ch

Please see link : Gwatt-Zentrum


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MAIN Science News:"Immune Cell Migration in Inflammation: present and future therapeu

Prof. Ronen Alon (Weizmann Institute of Science, Rehovot, Israel) and a Local Institute Co-Ordinator within the MAIN project has a paper to be published in the December issue of Nature Immunology entitled,

"Immune Cell Migration in Inflammation: present and future therapeutic targets"

together with co-authors Andrew D. Luster and Ulrich H. von Adrian.

Please click on the direct link to this article: click here


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MAIN Science News: “Professional Antigen-Presentation Function by Human gamma-delta T
Prof. Bernhard Moser of the Institute of Cell Biology, Switzerland and a Local Institute Co-Ordinator within the MAIN project, has a paper on the subject

“Professional Antigen-Presentation Function by Human gamma-delta T Cells”

published as a Research Article in ScienceExpress (2 June 2005)
http://www.sciencemag.org/cgi/content/abstract/1110267

(The printed version will appear in 4-6 weeks).

together with Marlène Brandes and Katharina Willimann all at the Institute of Cell Biology, University of Bern, CH-3012, Switzerland.

(E-mail correspondence: bernhard.moser@izb.unibe.ch)


Prof. Moser and his research team's overall goals are chemokines and their receptors in inflammatory cell migration.

Their major achievements to date include: IL-8 and related chemokines, structural and functional studies, Chemokine receptor cDNA isolation, expression and characterization, control of Effector T cell traffic, recognition that activated/effector but not resting/naïve T cells respond to inflammatory chemokines, HIV infection, discovery and role of chemokine receptors as HIV co-receptors, inhibition of entry by chemokines, Homeostatic chemokines, disease/inflammation-unrelated lymphocyte traffic, Adaptive immunity control of lymph node activities by chemokines.
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"MAIN Science News: How do rolling immune cells use their integrins to arrest on infl
Prof. Ronen Alon at the Weizmann Institute of Science, Rehovot, Israel and a Local Institute Co-Ordinator within the MAIN project, will have a paper on the subject " How do rolling immune cells use their integrins to arrest on inflamed blood vessels?" published in the forthcoming MAY issue of the prestigious journal NATURE IMMUNOLOGY.

Prof. Alon's research has involved exploring the molecular basis of leukocyte trafficking to specialized sites of immune cell activation and effector function within inflamed and lymphoid tissues (1, 2). The specific goal of  research is to unravel novel cellular machineries by which leukocyte adhesion receptors on effector lymphocytes rapidly integrate signals from endothelial targets allowing specific subsets of immune cells to adhere to and migrate through target endothelial sites under blood flow-derived shear forces.

Some of his team's major findings to date include: 1. The molecular basis of L-selectin function in shear flow and a novel regulatory role of chemokines in selectin adhesion (3, 4). 2. The elucidation of specific intracellular pathways in lymphocytes and monocytes which regulate integrin adhesiveness at inflamed endothelial contacts through altering integrin affinity and microclustering (5). 3. The discovery that endothelial-displayed chemokines regulate local clustering of leukocyte integrins at sub-second adhesive contacts through novel signaling pathways within confined lipid microdomains on the leukocyte surface.
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"MAIN science news: role of PI3k delta in allergy uncovered"

 
Dr. Bart Vanhaesebroek, (Ludwig Institute for Cancer Research in London, UK) and a Principal Investigator within the MAIN project has recently had the aforementioned paper published in the distinguished Journal NATURE (2004 Oct 21;431(7011):1007-11)  


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Postdoctoral Fellowship in vivo pharmacology
Job Description: Candidates must possess a PhD plus 4-10 years of relevant working experience in research. They must be nationals of the European Union or associated states. Nationals of Italy are excluded as are other EU citizens who have resided in Italy for 12 months during the last two years. The objective of the work will consist in the identification of novel targets and therapeutic approaches in chronic inflammatory diseases using animal models. The fellow should have a strong background and interest in models of inflammatory diseases, cellular and molecular immunology. The ideal candidate will have demonstrated ability to carry out independent research while being an effective teamplayer. More information on this position can be found at: http://www.euro-ra.de
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The External Advisory Board (EAB) for MAIN has now been defined

The External Advisory Board (EAB) for MAIN has now been defined. The Board will be chaired by Dr R. A. Horwitz of the University of Virginia.

Additional EAB members are Dr. Zena Werb, University of California San Francisco, Dr. Keith Burridge, University of North Carolina at Chapel Hill and Dr. Klaus Ley, University of Virginia.


Alan F.  "Rick" Horwitz  (Chair)                   WEB  Zena Werb    WEB Keith Burridge       WEB Klaus LeyWEB


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MAIN Annual Conference: 30th September - 2nd October 2005

Title: MAIN Annual Conference 2005
Date: 30th September (Welcome Dinner),1st-2nd October 2005 (Conference)
Location: San Raffaele Congress Centre, via Olgettina, 58, 20132 Milano: Download the Map of Milano2 here

Download the Conference Programme

The MAIN Annual Conference represents the prime opportunity for MAIN members to report on their progress in the various assignments comprised in the JPA. The Annual Conference will be attended by LICs, PIs and researchers. Data sessions will be paralleled by extensive poster presentations and followed by break-out sessions to plan future activities. The meeting will also be attended by members of the External Advisory Board and by representatives of the EU Commission.

The External Advisory Board (EAB) for MAIN has now been defined. The Board will be chaired by Dr. R. A. Horwitz of the University of Virginia.
Additional EAB members are Dr. Zena Werb, University of California San Francisco, Dr. Keith Burridge, University of North Carolina at Chapel Hill and Dr. Klaus Ley, University of Virginia
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“The Inflammatory Basis of Vascular Disease” 3rd- 4th February 2005, all day

Title:   “The Inflammatory Basis of Vascular Disease”
Date:   3rd - 4th February 2005, all day
Location:    Hammersmith Campus of Imperial College London               
                  Du Cane Road
                  London W12 ONN
                  UK
Contact: Maaike Van Steensel m.vansteensel@imperial.ac.uk

The symposium will have several sessions of direct interest to MAIN, including sessions on endothelial activation, endothelial cytoprotection, inflammatory cell signalling and leukocyte recruitment.


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First Annual Luminy advanced course on immunology and EMBO Workshop on "Future Direct
Between January 13th-15th 2005, the CIML, one of Europe’s leading research centres in fundamental immunology and immunopathology, is organising a series of four in-depth lectures aimed at doctoral and postdoctoral students in order to mark the opening of its new institute. These lectures will cover diverse aspects of recognition strategies in innate and adaptive immunity. In addition to the lecture course, a number of discussion groups led by CIML staff members will also be organised. Students attending the CIML grand opening event will be given access to the concomitant EMBO workshop: "The Road Ahead: Future Directions in Fundamental and Clinical Immunology"

Details for both events can be found HERE
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"Deciphering the Cell Migration Code" April 30th- May 3rd 2005

"Deciphering the Cell Migration Code", a meeting specifically for students, will take place at the Gwatt-Zentrum in Switzerland.

DATE:  Saturday, April 30th to Tuesday, May 3rd, 2005.

Located by the breathtaking Lake of Thun: at the Gwatt-Zentrum am Thunersee, CH-3645 Gwatt (Thun)
(30-40 km from Bern. Nearest stations: Spiez/Thun-c. 8km)

Tel. 033 334 30 30, Fax 033 334 30 31
mail@gwatt-zentrum.ch

Please see link : Gwatt-Zentrum


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LICs Conference, 7th-9th November 2004
Date: 7th-9th November, 2004 Location:  Schloss Munchenwiler, Munchenwiler/Murten 1797, Switzerland
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NIGMS Awards New LIPID Glue
Lipid research is the focus of the most recently funded NIGMS Glue Grant Initiative. This enteprise is headed by Principal Investigator Edward Dennis of the University of California at San Diego. One of the goals of this Consortium is to separate and detect all of the lipids in a specific cell and to discovery and characterize any novel lipids that may be present. For more information about the LIPID Metabolities And Pathways Strategy, LIPID MAPS, visit their web site at http://www.lipidmaps.org/
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Aims of the Network
Chronic inflammation is a systemic disorder resulting from the dysregulation of multiple, mechanistically unrelated higher order biological processes. The MAIN (Migration And Inflammation) Consortium, funded within the sixth framework program of the EU, will promote the integration of multi-disciplinary research groups to achieve a thorough understanding of directed inflammatory cell migration towards and across injured tissues. To achieve its goals, the MAIN Consortium will be based on four developmental Research Programs (Tool Development Program, Target Identification Program, Target Validation Program and Drug Development Program), three Support Facilities (Imaging, Proteomics and Microarrays) and one Core Facility (Bioinformatics). One of the research goals is to integrate specific knowledge and technological approaches to provide a unified explanation on how multiple inputs received by inflammatory cells result in spatially and temporally coordinated outputs, affecting the migratory behavior of such cells. To spread excellence through education and training, MAIN will implement a Training and Education Program (TEP), with practical courses and workshops for graduate students and technicians.
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Postdoctoral fellowship in vascular biology
Job Description:
Two postdoctoral fellowships are offered to study novel genes involved in endothelial cell migration and angiogenesis. The project deals with the use of genetically modified mouse and Zebra Fish embryos.


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Postdoctoral Position in Human Immunology
Job Description:
Current research activities deal with topics within human immunology and are focused on the interrelation between the localization and tissue distribution of leukocytes and their function in innate and adaptive immunity. The current working paradigm predicts that molecular cues on leukocytes, such as adhesion and chemokine receptors, predetermine leukocyte differentiation and inflammatory responses. The open position is funded by an EU Research Program for work within the areas of skin immunity, antigen-presentation and vaccination. The research group is strongly engaged in local and international collaborations and participates in several research networks. -------- Experimental experience in immunology, including cell isolation, tissue culture and flow cytometry, is mandatory. The present position fits a person who wishes to persue a career in immunology and biomedical research. -------- Please send your CV, including research interests and list of publications, and three letters of recommendations to the address below.


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Research Technician in the Vascular Science Section of the National Heart and Lung Di
Job Description:
Applications are invited for the position of Research Technician in the Vascular Science Section of the National Heart and Lung Division, within the Imperial College Faculty of Medicine based at the Hammersmith Campus located in East Acton. We are seeking an effective and motivated individual to join an intensely collaborative team of scientists interested in vascular biology and disease who are researching the role of junctional adhesion molecules, particularly ICAM-2, in angiogenesis (Huang et al Blood 106(5):1636-43, 2005). The project will involve cellular and molecular biology techniques, including developing cell lines and DNA constructs. The position also involves sharing responsibility for the routine management of the laboratory and for the daily maintenance of a Zeiss confocal microscope. Applicants should have experience in tissue culture and molecular biology and some experience in confocal microscopy would be desirable. The post will require collaborating with other groups within and outside the department. Closing date: 3 April 2006 Valuing diversity and committed to equality of opportunity


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Post Doctoral Research Associate in the Vascular Science Section of the National Hear
Job Description:
Applications are invited for the position of Post Doctoral Research Associate, in the Vascular Science Section of the National Heart and Lung Division, within the Imperial College Faculty of Medicine based at the Hammersmith Campus located in East Acton. We are seeking a highly motivated scientist to join an intensely collaborative team of basic and translational research scientists interested in vascular biology and disease. The aim of the project is to characterise a new angiogenesis pathway we recently described (Huang et al Blood 106(5):1636-43, 2005), involving the junctional adhesion molecule ICAM-2 and the small GTPase Rac. The project will require the use of molecular, biochemical and cell biology techniques including siRNA, retroviral vectors and confocal microscopy. Applicants should have experience in cellular and molecular biology with experience in endothelial cell biology, signalling and/or angiogenesis being desirable. The post will require collaborating with other groups within and outside the department. Closing date: 3 April 2006 Valuing diversity and committed to equality of opportunity


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