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Main-Noe Students Meeting - May 17-20th 2008, Certosa di Pontignano, Italy

MAIN Annual Conference, October 2007

MAIN LIC's Meeting, 9th March, 2007

MAIN Students' Meeting, 19th-22nd May, 2007

SEMM Workshop on Cell Migration: From Molecules to Organisms and Diseases

MAIN Science News: Paper published on "A novel protein on cells of the blood vessel w

 
 
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This is Topic: Breaking News

MAIN Annual Conference, October 2007
[url=http://www.main-noe.org/index.php?module=mnconference3]CLICK HERE TO ACCESS THE CONFERENCE BOOKING FORM[/url]

[url=http://www.main-noe.org/upload/Plano_Metro_2007.pdf]metro plan[/url]

DATE: 18th-20th October, 2007 in Madrid:

Thursday 18th (Welcome Buffet Dinner @ 20.30)
Conference all day Friday 19th-to & including lunch on Saturday 20th.
EAB, LIC's, Scientific Officer & External Reviewer's Meetings post-lunch
to c. 17.00.

LOCATION: Hotel Jardin Metropolitano
Reina Victoria 12, 28003 Madrid, Spain

Contact: Yolanda Garcìa
Tel: 0034911831810
Fax: 0034911831811
e-mail: metropolitano@vphoteles.com
http://www.bookings.org/hotel/es/jardin-metropolitano.en.html?aid=307713

Please CLICK HERE for the BOOKING FORM


Located in Avenida Reina Victoria, next to Cuatro Caminos Square & underground station and only 5 minutes from Paseo de la Castellana.

Transport from the Airport:

UNDERGROUND: Take the underground from Barajas Airport to Nuevos Ministerios Stop, and then change line to the Cuatro Caminos station (1 stop, see map: ). The Hotel is just by the Underground.
The underground ticket prices from T1, T2 and T3 of Barajas Airport are: 1 Euro and from the T4 are 2 Euros. There are also underground/bus tickets valid for 10 trips, which cost 6.40 Euros.

TAXIS: There is taxi service available from terminals at Barajas Airport.
The taxi fares range between 25-30 Euros, depending on the traffic. From the train station the taxi fares are a little lower, given that it is nearer the city center.

BUS: There are buses from all Terminals at Barajas Airport to Avenida de America and Plaza de Colon. Once there, you can take the underground to reach the hotel. From Avenida de America there is a direct underground line (line 6) to the hotel (Cuatro Caminos stop).

Transport from the Train Station:

From Chamartin Station, in the North of Madrid, you can take the underground to the Cuatro Caminos stop.
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MAIN Science News: Paper published on "A novel protein on cells of the blood vessel w
Dietmar Vestweber,  at the University of Muenster and LIC in MAIN has had an article on
"A novel protein on cells of the blood vessel wall involved in the regulation of the opening of cell contacts"
published in the prestigious Journal of Experimental Medicine, July 2006.

Vestweber & his teams' overall scientific goals include: understanding how leukocytes overcome the barrier of the blood vessel wall & how various known and unknown cell adhesion mechanisms mediate and control the opening and closure of endothelial cell contacts and the movement of leukocytes through the contact sites between endothelial cells.
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MAIN Science News: Paper published on the role of caveolae in the migration of human
Anne Ridley, Vice Co-Ordinator of MAIN & Local Institute Co-Ordinator at the Ludwig Institute for Cancer Research (LICR), has had a paper published in Nature Cell Biology.

Anne's team's overall goal is to understand how inflammatory stimuli affect endothelial cell biology. In addition, they aim to elucide the signalling pathways activated in T cells and in endothelial cells following their interaction. The overall aim is to identify key signalling proteins that could be targets for therapeutic intervention in chronic inflammation.
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MAIN Science News: “Follicular B Helper T Cells in Antibody Responses and Autoimmunit

Prof. Bernhard Moser of the Institute of Cell Biology, Switzerland and a Local Institute Co-Ordinator within the MAIN project, has had a paper on the subject

“Follicular B Helper T Cells in Antibody Responses and Autoimmunity”

published as a Research Article in Nature Reviews Immunology (November 2005)
http://www.nature.com/nri/journal/v5/n11/full/nri1714_fs.html

together with
Carola G. Vinuesa at the The John Curtin School of Medical Research, The Australian National University, Canberra, Australia;
Stuart G. Tangye at the Centenary Institute of Cancer Medicine and Cell Biology, Newton, Australia; and
Charles R. Mackay at The Garvan Institute of Medical Research, Sydney, Australia


(E-mail correspondence: bernhard.moser@izb.unibe.ch)


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MAIN Science News:"Immune Cell Migration in Inflammation: present and future therapeu

Prof. Ronen Alon (Weizmann Institute of Science, Rehovot, Israel) and a Local Institute Co-Ordinator within the MAIN project has a paper to be published in the December issue of Nature Immunology entitled,

"Immune Cell Migration in Inflammation: present and future therapeutic targets"

together with co-authors Andrew D. Luster and Ulrich H. von Adrian.

Please click on the direct link to this article: click here


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MAIN Science News: “Professional Antigen-Presentation Function by Human gamma-delta T
Prof. Bernhard Moser of the Institute of Cell Biology, Switzerland and a Local Institute Co-Ordinator within the MAIN project, has a paper on the subject

“Professional Antigen-Presentation Function by Human gamma-delta T Cells”

published as a Research Article in ScienceExpress (2 June 2005)
http://www.sciencemag.org/cgi/content/abstract/1110267

(The printed version will appear in 4-6 weeks).

together with Marlène Brandes and Katharina Willimann all at the Institute of Cell Biology, University of Bern, CH-3012, Switzerland.

(E-mail correspondence: bernhard.moser@izb.unibe.ch)


Prof. Moser and his research team's overall goals are chemokines and their receptors in inflammatory cell migration.

Their major achievements to date include: IL-8 and related chemokines, structural and functional studies, Chemokine receptor cDNA isolation, expression and characterization, control of Effector T cell traffic, recognition that activated/effector but not resting/naïve T cells respond to inflammatory chemokines, HIV infection, discovery and role of chemokine receptors as HIV co-receptors, inhibition of entry by chemokines, Homeostatic chemokines, disease/inflammation-unrelated lymphocyte traffic, Adaptive immunity control of lymph node activities by chemokines.
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"MAIN Science News: How do rolling immune cells use their integrins to arrest on infl
Prof. Ronen Alon at the Weizmann Institute of Science, Rehovot, Israel and a Local Institute Co-Ordinator within the MAIN project, will have a paper on the subject " How do rolling immune cells use their integrins to arrest on inflamed blood vessels?" published in the forthcoming MAY issue of the prestigious journal NATURE IMMUNOLOGY.

Prof. Alon's research has involved exploring the molecular basis of leukocyte trafficking to specialized sites of immune cell activation and effector function within inflamed and lymphoid tissues (1, 2). The specific goal of  research is to unravel novel cellular machineries by which leukocyte adhesion receptors on effector lymphocytes rapidly integrate signals from endothelial targets allowing specific subsets of immune cells to adhere to and migrate through target endothelial sites under blood flow-derived shear forces.

Some of his team's major findings to date include: 1. The molecular basis of L-selectin function in shear flow and a novel regulatory role of chemokines in selectin adhesion (3, 4). 2. The elucidation of specific intracellular pathways in lymphocytes and monocytes which regulate integrin adhesiveness at inflamed endothelial contacts through altering integrin affinity and microclustering (5). 3. The discovery that endothelial-displayed chemokines regulate local clustering of leukocyte integrins at sub-second adhesive contacts through novel signaling pathways within confined lipid microdomains on the leukocyte surface.
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"MAIN science news: role of PI3k delta in allergy uncovered"

 
Dr. Bart Vanhaesebroek, (Ludwig Institute for Cancer Research in London, UK) and a Principal Investigator within the MAIN project has recently had the aforementioned paper published in the distinguished Journal NATURE (2004 Oct 21;431(7011):1007-11)  


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NIGMS Awards New LIPID Glue
Lipid research is the focus of the most recently funded NIGMS Glue Grant Initiative. This enteprise is headed by Principal Investigator Edward Dennis of the University of California at San Diego. One of the goals of this Consortium is to separate and detect all of the lipids in a specific cell and to discovery and characterize any novel lipids that may be present. For more information about the LIPID Metabolities And Pathways Strategy, LIPID MAPS, visit their web site at http://www.lipidmaps.org/
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